Abstract:
We assessed the antiviral actvity of several C-glycosides (C-glycosil-furane,
C-glycosilpirimidines and C-glycosilnorbornenes) against 3 strains of herpes virus I, 2 strains of herpes virusII,
1 strainof varicella-zoster virus, 2 strains of enterovirus, 3 stains of syncitial respiratory virus, 2 strains of adenovirus and one
strain of rhinovirus, by using a viral cytopathic effect reduction test. The cytopathic effects of herpes virus I and herpes virus II
were inhibited by one the C-glycosifurane [2-(2,3-O-isopropylidene-b-D-
-eritrofuranosil)-4-ethoxycharbonyl-5-methylfurane) (J-2) at a concentration of 400mg/ml.