Mitonafide and Amonafide

Braña, F.M.

Departamento de Química Farmacéutica. Universidad de San Pablo CEU. Madrid.España

Ars Pharm.36;(3);377-415, (1995)

Key words:Mitonafide, Amonafide, Intercalant agents

Abstract

The naphthalimides are a family of new intercalator agents with antitumor properties. Here, we describe the design, synthesis and chemotherapeutic activity, together with the results of preclinical studies in order to initiate the clinical essays.

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